What is Biomedical Engineering?

Biomedical engineering is an emerging research focus. Researchers in this theme are leveraging our proximity to Australia’s foremost biomedical sciences and clinical research precinct to pursue research and development opportunities where engineering expertise is essential to address clinically meaningful problems.

These projects are pursued via collaborations with institutions such as National ICT Australia (NICTA’s ICT for Life Sciences program), Hugh Williamson Gait Analysis Laboratory at the Royal Children’s Hospital, Bio21, Walter and Eliza Hall Institute, Ludwig Cancer Institute, Murdoch Children’s Research Institute, St Vincent’s Hospital Melbourne, the Howard Florey Institute and the Bionic Ear Institute.

Theme Leader

Professor Anthony Burkitt

Programs

Key programs within this research theme include:

---

---

By fully integrating medicine, biology and engineering principles, biomedical engineering aims to provide a better understanding of the body and how to treat diseases. For example, researchers are working on a model to accurately assess knee joint stress in people with and without knee osteoarthritis. The accurate prediction of joint loads will assist in the management of disease and inform physiotherapy and surgical treatment. Other applications of this technology include evaluating the performance of total joint replacements so that biomedical engineers can improve on current implant designs.

Another project that demonstrates a truly interdisciplinary research approach focuses on the prediction of epileptic seizures. This could be used to activate an implantable device that can prevent or abort epileptic seizures or to target drug delivery to the site of the seizure. The exact cause of epileptic seizures in the brain is not well understood, and researchers in this group are trying to understand the underlying causes of epilepsy through both physiological experiments and neural modelling.

Other research interests in this theme involve areas related to biotechnology. Bones, muscles, blood vessels and skin all contain proteins. Proteins have chain molecules which assemble and fold into very particular shapes to serve their intended purpose. Alzheimer’s disease, type 2 diabetes and heart disease are all associated with abnormalities in protein behaviour, such as proteins not assembling or folding properly. Protein therapeutics is the fastest growing area in biotechnology but some apparently good treatments are rendered useless by protein misfolding. The objective of our research is to understand the key factors that cause these protein therapies to not work as expected; this is critical to the successful commercialisation of these treatments.

Research Staff

Research Staff	Email
Professor Anthony Burkitt (Theme Leader)
Ahsan Khandoker
Andrew Ooi
Iven Mareels
Anthony Schache
Arthur Hsu
Bruce Gardiner
David Dunstan
David Grayden
Edmund Kazmierczak
Frank Caruso
Guillermo Narsilio
Hyung Kim
Jayavardhana Gubbi Lakshminarasimha
Jonathan Merritt
Karlis Gross
Leigh Johnston
Leslie Kitchen
Levin Kuhlmann
Linda Stern
Marcus Pandy
Marimuthu Palaniswami
Malka Halgamuge
Paul Hamilton-Brown
Peter Stuckey
Rao Kotagiri
Saman Halgamuge
Slaven Marusic
Udaya Gunasekara Karumpullige